OCS™ Lung TOP Registry For Donor Lungs for Transplantation

Active, not recruitingOBSERVATIONAL
Enrollment

458

Participants

Timeline

Start Date

December 10, 2018

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2029

Conditions
Lung Transplantation
Interventions
DEVICE

OCS Lung System

"The OCS™ Lung System is a portable organ perfusion, ventilation, and monitoring medical device intended to preserve donor lungs in a near physiologic, ventilated, and perfused state prior to transplantation. This technology was designed to overcome the limitation of cold storage and has the potential to expand the utilization of donor lungs. The OCS™ Lung System accomplishes this by performing 3 key functions:~* Reducing ischemic injury through the use of warm, oxygenated blood based perfusion.~* Optimizing the lung condition by ventilatory recruitment maneuvers and high-oncotic perfusion solution supplemented with hormones and nutrients.~* Allowing for ex-vivo functional assessment of the donor lung during preservation and prior to transplant."

Trial Locations (18)

19140

Temple University, Philadelphia

21218

Johns Hopkins, Baltimore

27710

Duke University, Durham

30322

Emory, Atlanta

33606

Tampa General Hospital, Tampa

48202

Henry Ford Health System, Detroit

53226

Medical College of Wisconsin, Milwaukee

55455

University of Minnesota, Minneapolis

60637

University of Chicago, Chicago

68198

Nebraska Medical Center, Omaha

75204

Baylor Scott & White Research Institute, Dallas

77030

Baylor St. Luke's Medical Center, Houston

Houston Methodist, Houston

85013

St. Joseph's Hospital and Medical Center, Phoenix

90095

UCLA, Los Angeles

94143

UCSF, San Francisco

94304

Stanford University, Palo Alto

02114

Massachusetts General Hospital, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

TransMedics

INDUSTRY

NCT03639025 - OCS™ Lung TOP Registry For Donor Lungs for Transplantation | Biotech Hunter | Biotech Hunter