Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC

PHASE2UnknownINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

May 1, 2019

Primary Completion Date

October 31, 2020

Study Completion Date

January 31, 2021

Conditions
Pancreatic Ductal AdenocarcinomaPancreatic CancerPancreatic Neoplasms
Interventions
DRUG

PEGPH20

PEGPH20 is a PEGylated, neutral-pH-active human hyaluronidase PH20 produced by recombinant DNA technology

BIOLOGICAL

Pembrolizumab

Pembrolizumab is a potent and highly selective humanized monoclonal antibody (mAb) of the IgG4/kappa isotype designed to directly block the interaction between PD-1 and its ligands, PD-L1 and PD-L2

Trial Locations (5)

53226

RECRUITING

Medical College of Wisconsin, Milwaukee

80048

NOT_YET_RECRUITING

Cedars Sinai Medical Center, Los Angeles

85234

NOT_YET_RECRUITING

Banner Health - MD Anderson Cancer Center, Gilbert

98101

RECRUITING

University of Washington--Seattle Cancer Care Alliance, Seattle

08901

ACTIVE_NOT_RECRUITING

Rutgers - Cancer Institute of New Jersey (CINJ), New Brunswick

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Halozyme Therapeutics

INDUSTRY

collaborator

University of Washington

OTHER

lead

Pancreatic Cancer Research Team

OTHER

NCT03634332 - Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC | Biotech Hunter | Biotech Hunter