NCT03630211View on ClinicalTrials.gov

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

PHASE2RecruitingINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

July 31, 2018

Primary Completion Date

August 1, 2026

Study Completion Date

August 1, 2026

Conditions
Systemic SclerosisDiffuse Sclerosis SystemicInterstitial Lung DiseasePulmonary Hypertension
Interventions
DRUG

Cyclophosphamide

Stem Cell Mobilization

DRUG

Mesna

Stem Cell Mobilization

DRUG

Rituximab

Transplantation Conditioning

DRUG

Alemtuzumab

Transplantation Conditioning

DRUG

Thiotepa

Transplantation Conditioning

DRUG

GM-CSF

Transplantation Conditioning

DRUG

Intravenous immunoglobulin

Transplantation Conditioning

RADIATION

Total Body Irradiation

Transplantation Conditioning

DRUG

Anti Thymocyte Globulin

Transplantation Conditioning

Trial Locations (3)

15213

RECRUITING

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

15261

RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

All Listed Sponsors
lead

Paul Szabolcs

OTHER