A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies

PHASE1CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

September 12, 2018

Primary Completion Date

January 23, 2025

Study Completion Date

January 23, 2025

Conditions
Solid Tumor, Unspecified, Adult
Interventions
DRUG

Domvanalimab

Domvanalimabis a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting human TIGIT

DRUG

Zimberelimab

Zimbererlimab is a fully human immunoglobulin G4 (IgG4) monoclonal antibody targeting human PD-1

Trial Locations (10)

2010

The Kinghorn Cancer Centre - St Vincent Public Hospital, Darlinghurst

2486

Tweed Hospital, Tweed Heads

3084

Olivia Newton-John Cancer Research Institute-Austin Hostipal, Heidelberg

4101

Icon Cancer Care Brisbane, South Brisbane

28078

Carolina BioOncology Institute, Huntersville

60521

Affinity Health-Hope and Healing Cancer Services, LLC, Hinsdale

77030

MD Anderson Cancer Center, Houston

78229

START, San Antonio

90025

The Angeles Clinic and Research Institute, Los Angeles

99208

Medical Oncology Associates, PS (dba Summit Cancer Centers), Spokane

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Gilead Sciences

INDUSTRY

lead

Arcus Biosciences, Inc.

INDUSTRY