257
Participants
Start Date
August 1, 2018
Primary Completion Date
August 31, 2026
Study Completion Date
August 31, 2026
pembrolizumab
Age 10-17: 2mg/kg (cap at 200mg), Age ≥ 18: 200 mg (flat) ,Day 1 of each 3 week cycle IV infusion 2-4 cycles (pre-ASCT)
gemcitabine
1000mg/m\^2 Days 1 and 8 of each 3 week cycle IV infusion 2-4 cycles
vinorelbine
20mg/m\^2 Days 1 and 8 of each 3 week cycle IV infusion 2-4 cycles
liposomal doxorubicin
15mg/m\^2 Days 1 and 8 of each 3 week cycle IV infusion 2-4 cycles
Stem cell mobilization and collection
Stem cell mobilization and collection will be performed as per standard MSKCC guidelines after 2-4 cycles of pembrolizumab-GVD.
RECRUITING
Memorial Sloan Kettering Cancer Center, New York
RECRUITING
Memorial Sloan Kettering Westchester, Harrison
RECRUITING
Memorial Sloan Kettering Nassau, Uniondale
RECRUITING
Memorial Sloan Kettering Cancer Center @ Commack, Commack
RECRUITING
University of Miami, Miami
RECRUITING
Memorial Sloan Kettering Basking Ridge, Basking Ridge
RECRUITING
Memorial Sloan Kettering Monmouth, Middletown
RECRUITING
Memorial Sloan Kettering Bergen, Montvale
Merck Sharp & Dohme LLC
INDUSTRY
Memorial Sloan Kettering Cancer Center
OTHER