NCT03609775 - A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy Subjects | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 28, 2018

Primary Completion Date

October 9, 2018

Study Completion Date

October 9, 2018

Conditions

Healthy

Interventions

DRUG

ACT-541468

One tablet of 50 mg ACT-541468 will be administered orally.

OTHER

ACT-541468 placebo

Matching ACT-541468 placebo will be administered orally as 1 tablet.

OTHER

Ethanol 10%

Ethanol 10% w/v solution in 5% glucose will be administered i.v. for 5 h and clamped at an ethanol level of 0.6 g/L.

OTHER

Ethanol placebo

Matching placebo for the ethanol infusion (i.e., 5% glucose solution) will be administered i.v. for 5 h.

Trial Locations (1)

Centre For Human Drug Research, Leiden