96
Participants
Start Date
July 25, 2018
Primary Completion Date
June 12, 2020
Study Completion Date
June 12, 2020
NNC0174-0833
Participants will receive increasing dose levels of 0.16 mg, 0.3 mg, 0.6 mg, 1.2 mg, 2.4 mg or 4.5 mg of NNC0174-0833 (subcutaneous \[s.c.\], in a lifted fold of the abdominal skin) injection once weekly starting with a very low dose and then escalated every 4 weeks to a slightly higher dose each time. Each participant will only be given one dose level.
Semaglutide
Participants will receive 2.4 mg of semaglutide (s.c., in a lifted fold of the abdominal skin) injection once weekly starting with a very low dose and then escalated every 4 weeks to a slightly higher dose each time.
Placebo (NNC0174-0833)
Participants will receive once weekly injections of NNC0174-0833 matched placebo.
Novo Nordisk Investigational Site, Overland Park
Lead Sponsor
Novo Nordisk A/S
INDUSTRY