Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) Subjects

PHASE2TerminatedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

August 7, 2018

Primary Completion Date

August 3, 2022

Study Completion Date

August 3, 2022

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

ATG-008

Approximately 20 subjects will receive oral ATG-008 at an initial dose of 45 mg/QD and another 20 subjects will receive oral ATG-008 at an initial dose of 20mg/BID for 28 days each cycle.

Trial Locations (30)

150000

Oncology Hospital of Haerbin Medical University, Harbin

210000

China People PLA 81 Hospital, Nanjing

610041

West China Hospital Sichuan University, Chengdu

650118

Yunnan Cancer Hospital, Kunming

Unknown

The first Hospital of Jilin University, Changchun

Hunan Province Oncology Hospital, Changsha

Daping Hospital, Chongqing

The first hospital of Chongqing medical university, Chongqing

Xiehe Hospital of Fujian Medical University, Fuzhou

Nanfang Hospital of Nanfang Medical University, Guangzhou

The first affiliated Hospital of Zhejiang University, Hangzhou

Zhejiang Province Oncology Hospital, Hangzhou

The first affiliated hospital of Anhui medical university, Hefei

The second affiliated hospital of Anhui medical university, Hefei

The first affiliated hospital of Guangxi Medical University, Nanning

Oncology Hospital of Fudan University, Shanghai

Zhongshan Hospital of Fudan University, Shanghai

General Hospital of the Northern War Zone of the Chinese People's Liberation Army, Shenyang

Tangdu Hospital of China PLA fourth medical university, Xi'an

Dong-A University Hospital, Busan

Pusan National Univ. Hospital, Busan

Kyungpook National Univ. Hospital, Daegu

Asan Medical Center, Seoul

Seoul National University Hospital, Seoul

Severance Hospital, Yonsei University Health System, Seoul

China Medical University Hospital, Taichung

National Taiwan University Hospital, Taipei

Taipei Medical University Hospital, Taipei

Taipei Veterans General Hospital, Taipei

Chang Gung Memorial Hospital-Linkuo, Taoyuan District

Sponsors
All Listed Sponsors
lead

Antengene Therapeutics Limited

INDUSTRY

NCT03591965 - Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) Subjects | Biotech Hunter | Biotech Hunter