25
Participants
Start Date
October 1, 2018
Primary Completion Date
December 31, 2025
Study Completion Date
March 31, 2028
Summit RC+S for Motor
Using the RC+S pulse generator, investigators will measure cortical biomarkers of hyper and hypokinesia in Parkinson's and dystonia patients to develop an adaptive algorithm which adjusts the level of deep brain stimulation needed based upon the patient's physiology.
8-week pilot trial of Closed-loop vs. Open-loop Stimulation
These patients will participate in an 8 week clinical trial of open loop versus adaptive mode (4 weeks for each mode (interleaved), with the order counterbalanced across subjects ).
Summit RC+S for Sleep
Using the RC+S pulse generator, investigators will measure cortical biomarkers of sleep stages in Parkinson's patients to develop an adaptive algorithm which adjusts the level of deep brain stimulation needed based upon the patient's physiology.
University of California at San Francisco, San Francisco
University of California, San Francisco
OTHER