Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 6, 2020

Primary Completion Date

June 6, 2027

Study Completion Date

June 6, 2027

Conditions
Systemic SclerosisDermatomyositisiPPSD2
Interventions
DRUG

STS

"M0-M6 (run-in phase): medical care and follow-up as usual~M6-M12 (STS phase):~* Patients with iPPSD2 will be treated with subcutaneous infusion using a portable pump.~* Patients with dermatomyositis or systemic sclerosis will be treated with repeated injections every two weeks.~Patients will receive a maximal total number of 11 STS injections. M12: final visit (V5): clinical evaluation, photograph and CT scan of the treated lesion, pain and quality of life evaluation."

Trial Locations (8)

31000

RECRUITING

CHU de Toulouse, Toulouse

33000

RECRUITING

CHU de BORDEAUX, Bordeaux

69500

NOT_YET_RECRUITING

Hospice Civil de Lyon, Bron

75000

RECRUITING

ApHp - hôpital Lariboisière, Paris

75651

NOT_YET_RECRUITING

Hôpital de la Pitié Salpétriêre, Paris

76031

NOT_YET_RECRUITING

CHU de ROUEN, Rouen

87042

RECRUITING

CHU de Limoges, Limoges

94270

RECRUITING

ApHp - Hôpital Bicêtre, Le Kremlin-Bicêtre

All Listed Sponsors
lead

University Hospital, Limoges

OTHER