A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of IONIS FXI-LRx in up to 84 Healthy Volunteers

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

July 9, 2018

Primary Completion Date

April 26, 2019

Study Completion Date

April 26, 2019

Conditions

Healthy Participants

Interventions

DRUG

IONIS FXI-LRx

Ascending single and multiple doses of IONIS FXI-LRx by subcutaneous (SC) injection

DRUG

Placebo

Sterile Normal Saline (0.9% NaCl) calculated volume to match active comparator

Trial Locations (1)

BioPharma Services Inc., Toronto