NCT03581877View on ClinicalTrials.gov

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

January 28, 2019

Primary Completion Date

March 19, 2023

Study Completion Date

March 19, 2025

Conditions
Pulmonary EmbolismPulmonary HypertensionThromboembolismRight Ventricular Dysfunction
Interventions
DRUG

Alteplase

As stated before, low dose r-tpa will be administered through a peripheral vein for PLST.

DEVICE

EKOS

As stated before, the EKos device will be used for ultrasound assisted catheter directed thrombolysis or ACDT, same dose t-tpa will administered through the pulmonary catheter. It will be given at a fixed dose over 24 hours.

Trial Locations (2)

11040

Long Island Jewish Medical Center, Queens

11706

Southside Northwell Hospital, Bay Shore

Sponsors

Lead Sponsor

Northwell Health
All Listed Sponsors
lead

Northwell Health

OTHER