A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection

PHASE2CompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

June 11, 2018

Primary Completion Date

July 5, 2019

Study Completion Date

July 5, 2019

Conditions
Chronic Hepatitis B
Interventions
DRUG

ABI-H0731

Participants will receive ABI-H0731 300 mg tablets orally once daily (QD).

DRUG

SOC NUC

Participants will continue on their SOC NUC (ETV, TDF or TAF) tablet orally as per approved package insert.

DRUG

Placebo Oral Tablet

Participants will receive placebo matching ABI-0731 tablets orally QD.

Trial Locations (21)

10016

NYU Langone Health, New York

10029

Icahn School of Medicine at Mount Sinai, New York

11354

Sing Chan, MD, Flushing

19107

Thomas Jefferson University Hospital, Philadelphia

Xiaoli Ma, MD, Philadelphia

21228

Digestive Disease Associates, Catonsville

21287

Johns Hopkins University School of Medicine, Baltimore

33136

University of Miami Hospital and Clinics, Miami

90057

Asia Pacific Liver Center, Los Angeles

90095

University of California Los Angeles, Los Angeles

90211

Cedars-Sinai Medical Center, Beverly Hills

92105

Research and Education, San Diego

92118

Southern California Research Center, Coronado

92123

Medical Associates Research Group, San Diego

94115

Quest Clinical Research, San Francisco

94305

Stanford University Medical Center, Stanford

08844

Infectious Disease Care, Hillsborough

Unknown

Toronto General Hospital, Toronto

Toronto Liver Center, Toronto

GI Research Institute, Vancouver

Auckland City Hospital, Auckland

Sponsors
All Listed Sponsors
lead

Assembly Biosciences

INDUSTRY

NCT03576066 - A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection | Biotech Hunter | Biotech Hunter