Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study

NACompletedINTERVENTIONAL
Enrollment

177

Participants

Timeline

Start Date

September 3, 2018

Primary Completion Date

September 30, 2022

Study Completion Date

December 31, 2022

Conditions
Diabetes InsipidusPolydipsia, Primary
Interventions
DIAGNOSTIC_TEST

Arginine infusion

Intravenous Infusion of Arginine is given, copeptin measurement will be collected before and 60minutes after start of infusion

DIAGNOSTIC_TEST

Hypertonic saline infusion

Intravenous Infusion of hypertonic Saline is given, copeptin measurement will be collected before and once Plasma sodium rises above 149mmol/l

Trial Locations (7)

4031

University Hospital Basel, Department of Endocrinology, Basel

Unknown

Hospital das clinicas Minas Gerais, Belo Horizonte

University Hospital Würzburg, Würzburg

Granda Ospedale Maggiore Policlinico Milan, Milan

Erasmus MC, Rotterdam

University Hospital Zurich, Zurich

Cambridge University Hospital, Cambridge

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University Hospital, Zürich

OTHER

collaborator

Wuerzburg University Hospital

OTHER

collaborator

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Cambridge University Hospitals NHS Foundation Trust

OTHER

collaborator

Federal University of Minas Gerais

OTHER

lead

University Hospital, Basel, Switzerland

OTHER

NCT03572166 - Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study | Biotech Hunter | Biotech Hunter