A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale

PHASE2CompletedINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

June 29, 2018

Primary Completion Date

June 14, 2019

Study Completion Date

June 14, 2019

Conditions
Osteoarthritis, Knee
Interventions
DRUG

Naproxen Sodium (Aleve, BAY117031)

660 mg daily for 3 days, 440 mg on the fourth day, over-encapsulated tablet, oral (Treatment A)

DRUG

Acetaminophen ER

3900 mg daily for 3 days, 1300 mg on the fourth day, over-encapsulated extended release (ER) tablet, oral (Treatment B)

DRUG

Celecoxib

200 mg daily for 3 days, 100 mg on the fourth day, over-encapsulated capsule, oral (Treatment C)

DRUG

Placebo

Over-encapsulation capsule, 4 days, oral (Treatment D)

Trial Locations (5)

33781

Radiant Research, Inc., Pinellas Park

45236

Radiant Research, Inc., Cincinnati

60602

Radiant Research, Inc., Chicago

78229

Radiant Research, Inc., San Antonio

85224

Radiant Research, Inc., Chandler

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY