500
Participants
Start Date
January 1, 2012
Primary Completion Date
December 31, 2018
Study Completion Date
December 31, 2018
Reoxygenation
After one minute of full bypass, fraction of inspired oxygen (FiO2) in conservative group was increased at increments of 0.1 per minute to reach an FiO2 target of 40% that was adjusted to maintain an arterial PO2 in the range of 250 mm Hg or less during the bypass, while FiO2 in liberal group was increased at increments of 0.1 per minute to reach a FiO2 target of 80% adjusted to maintain PO2 in the range of 300 mm Hg or more, on the basis of arterial PO2 level measured via a point of care blood gas analyzer.
RECRUITING
TEDA International Cardiovascular Hospital, Tianjin
Lead Sponsor
Nanjing Medical University
OTHER