Effects of LRYGB on Pharmacokinetics of Nine CYP Probe Drugs

NACompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

January 27, 2012

Primary Completion Date

December 10, 2014

Study Completion Date

December 10, 2014

Conditions
Obesity, MorbidBariatric Surgery Candidate
Interventions
DRUG

cocktail of nine CYP probe drugs

"Two equally loaded capsules containing:~Melatonin (2.0 mg) Nicotine (1.0 mg) Bupropion (37.5 mg) Repaglinide (0.25 mg) Losartan (12.5 mg) Omeprazole (10 mg) Chlorzoxazone (62.5 mg) Midazolam (1.85 mg) Dextromethorphan (30 mg) as an oral solution was administered separately after the capsules."

Trial Locations (1)

Unknown

University of Eastern Finland, Kuopio

Sponsors
All Listed Sponsors
collaborator

Diabetes Research Foundation, Finland

OTHER

collaborator

Finnish Cultural Foundation

OTHER

collaborator

Kuopio University Hospital

OTHER

collaborator

Academy of Finland

OTHER

lead

University of Eastern Finland

OTHER