NCT03563157 - QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 28, 2018

Primary Completion Date

April 21, 2019

Study Completion Date

August 21, 2019

Conditions

Colorectal Cancer MetastaticmCRC

Interventions

BIOLOGICAL

Aldoxorubicin Hydrochloride

Aldoxorubicin Hydrochloride HCI

BIOLOGICAL

ALT-803

Recombinant human super agonist interleukin-15 (IL-15) complex \[also known as IL-15N72D;IL-15RaSu/IgG1 Fe complex1\]

BIOLOGICAL

ETBX-011

Ad5 \[E1-, E2b-\]-CEA

BIOLOGICAL

ETBX-021

Ad5 \[E1-, E2b-\]-\[HER2\]

BIOLOGICAL

ETBX-051

Ad5 \[E1-, E2b-\]-Brachyury

BIOLOGICAL

ETBX-061

Ad5 \[E1-, E2b-\]-mucin 1 \[MUC1\]

BIOLOGICAL

GI-4000

RAS yeast

BIOLOGICAL

GI-6207

CEA yeast

BIOLOGICAL

GI-6301

Brachyury yeast

BIOLOGICAL

haNK

haNK™, NK-92 \[CD16.158V, ER IL-2\]

DRUG

Avelumab

BAVENCIO® injection

DRUG

Capecitabine

XELODA® tablets

DRUG

Cetuximab

ERBITUX® injection

DRUG

Cyclophosphamide

Cyclophosphamide Capsules

DRUG

5-Fluorouracil

5-FU; Fluorouracil Injection

DRUG

Leucovorin

Leucovorin Calcium

DRUG

Nab-paclitaxel

ABRAXANE® for Injectable Suspension \[paclitaxel protein-bound particles for injectable suspension\] \[albumin-bound\]

DRUG

Oxaliplatin

ELOXATIN® injection

DRUG

Regorafenib

STIVARGA® tablets

PROCEDURE

SBRT

Stereotactic body radiation therapy

Trial Locations (1)

90245

Chan Soon-Shiong Institute for Medicine, El Segundo