Tranexamic Acid in Adult Spinal Deformity Surgery

PHASE3RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 11, 2018

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Spinal DeformityDegenerative Lumbar Spinal StenosisBlood Loss, Surgical
Interventions
DRUG

Tranexamic Acid 100 MG/ML

TXA lavage solution (200 cc sterile normal saline + 5 g tranexamic acid 100mg/ml (50cc)) will be poured into the surgical field and left in contact for five minutes. This will occur after instrumentation. Excess solution will be suctioned away using a non-cell saver suction.

DRUG

Placebo

Placebo solution (200 cc sterile normal saline + placebo TXA ampule (50cc)) will be poured into the surgical field and left in contact for five minutes. This will occur after pedicle screw instrumentation. Excess solution will be suctioned away using a non-cell saver suction.

Trial Locations (1)

10021

RECRUITING

Hospital for Special Surgery, New York

All Listed Sponsors
lead

Hospital for Special Surgery, New York

OTHER

NCT03553186 - Tranexamic Acid in Adult Spinal Deformity Surgery | Biotech Hunter | Biotech Hunter