A Study to Look at the Effect MEDI0382 Has on Blood Sugar in People With Type 2 Diabetes and Kidney Problems and Also to Check That MEDI0382 is Well Tolerated

PHASE2CompletedINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

June 29, 2018

Primary Completion Date

February 4, 2019

Study Completion Date

February 4, 2019

Conditions
Type II Diabetes MellitusRenal Insufficiency
Interventions
DRUG

MEDI0382

Participants will receive subcutaneous MEDI0382 titrated from 50 μg upto 300 μg (50 μg once daily for 4 days, followed by 100 μg daily for 7 days, 200 μg daily for 7 days, and 300 μg daily for 14 days) for 32 days.

DRUG

Placebo

Participants will receive SC placebo matched to MEDI0382 once daily for 32 days.

Trial Locations (7)

10117

Research Site, Berlin

39120

Research Site, Magdeburg

48145

Research Site, Münster

81241

Research Site, München

DD1 9SY

Research Site, Dundee

EH16 4SA

Research Site, Edinburgh

EH4 2XU

Research Site, Edinburgh

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MedImmune LLC

INDUSTRY

NCT03550378 - A Study to Look at the Effect MEDI0382 Has on Blood Sugar in People With Type 2 Diabetes and Kidney Problems and Also to Check That MEDI0382 is Well Tolerated | Biotech Hunter | Biotech Hunter