Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor

PHASE4CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

June 15, 2024

Study Completion Date

June 30, 2024

Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
DRUG

isosorbide mononitrate

40 mg tablet of intra-vaginal IMN (Effox; MINAPHARMA, Cairo, Egypt) will be placed into the posterior fornix of the vagina, through a digital vaginal examination, every 4 h for a maximum of four doses.

DRUG

Placebos

In placebo group (group 2) 40 mg intra-vaginal pyridoxine placebos every 4 h for a maximum of four doses will be given

Trial Locations (1)

Unknown

faculty of medicine - Kafr Elsheikh university, Kafr ash Shaykh

All Listed Sponsors
collaborator

Kafrelsheikh University

OTHER

lead

ahmed nagy shaker ramadan

OTHER

NCT03544606 - Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor | Biotech Hunter | Biotech Hunter