Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

July 12, 2018

Primary Completion Date

December 1, 2024

Study Completion Date

July 1, 2026

Conditions
Chronic Lymphocytic LeukemiaRichter Syndrome
Interventions
DRUG

Duvelisib

This drug is designed to stop cancer growth by blocking a protein called phosphatidylinositide 3-kinase (PI3K), which is important for the survival of CLL cells.

DRUG

Venetoclax

Venetoclax targets a protein called BCL-2, which helps cancer cells survive.

Trial Locations (7)

33136

University of Miami- Sylvester Comprehensive Cancer Center, Miami

04412

Northern Light Eastern Maine Medical Center, Brewer

02114

Massachusetts General Hospital, Boston

02118

Boston Medical Center, Boston

02215

Beth Israel Deaconess Medical Center, Boston

Dana Farber Cancer Institute, Boston

01201

Berkshire Medical Center, Pittsfield

All Listed Sponsors
collaborator

Secura Bio, Inc.

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER

NCT03534323 - Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS | Biotech Hunter | Biotech Hunter