Nivolumab Plus Ramucirumab in Patients With Recurrent, Advanced, Metastatic NSCLC

PHASE2RecruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

October 8, 2020

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2027

Conditions
Non Small Cell Lung Cancer
Interventions
DRUG

Nivolumab

The treatment will be given on a 28-day cycle, with doses of nivolumab and ramucirumab given on days 1 and 15. The dose of nivolumab will be fixed at 240 mg. Nivolumab should be administered first, followed by premedication, and then ramucirumab. Ramucirumab should be administered approximately 30 minutes after premedication

DRUG

Ramucirumab

The treatment will be given on a 28-day cycle, with doses of nivolumab and ramucirumab given on days 1 and 15. The dose of ramucirumab will depend upon the patient weight as noted below. Nivolumab should be administered first, followed by premedication, and then ramucirumab. Ramucirumab should be administered approximately 30 minutes after premedication

Trial Locations (2)

10016

RECRUITING

NYU Langone, New York

19111

RECRUITING

Fox Chase Cancer Center, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

collaborator

Eli Lilly and Company

INDUSTRY

lead

Fox Chase Cancer Center

OTHER

NCT03527108 - Nivolumab Plus Ramucirumab in Patients With Recurrent, Advanced, Metastatic NSCLC | Biotech Hunter | Biotech Hunter