Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity

PHASE2CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

November 29, 2017

Primary Completion Date

August 31, 2021

Study Completion Date

August 31, 2021

Conditions
Obesity
Interventions
DRUG

Liraglutide

Initiate at 0.6mg S.C. daily for 1 week; subjects will return to the Clinical Research Unit (CRU) each week until an increase by 0.6mg/day in weekly intervals to a dose of 3.0 mg/day is achieved (\~4 weeks). Once maintenance dose of 3.0 mg is achieved, subjects will return approximately every 4 weeks to obtain new supply of study medication.

DRUG

Placebo

Placebo administration will match the study drug.

Trial Locations (1)

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

Novo Nordisk A/S

INDUSTRY

lead

Michael Camilleri, MD

OTHER