A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

PHASE1TerminatedINTERVENTIONAL
Enrollment

83

Participants

Timeline

Start Date

August 27, 2018

Primary Completion Date

September 10, 2025

Study Completion Date

September 10, 2025

Conditions
Advanced Solid Tumors
Interventions
DRUG

INCB081776

INCB081776 administered once or twice daily orally with water after a fast of at least 2 hours before and at least 1 hour after the dose.

DRUG

INCMGA00012

INCMGA0012 administered intravenously according to the label as 500 mg every 4 weeks

Trial Locations (18)

10065

Memorial Sloan Kettering Cancer Center, New York

15232

University of Pittsburgh, Pittsburgh

19104

University of Pennsylvania Abramson Cancer Center, Philadelphia

22185

Skane University Hospital Lund, Lund

37203

Sarah Cannon Research Institute, Nashville

53792

University of Wisconsin Carbone Cancer Center, Madison

77030

Md Anderson Cancer Center, Houston

06510

Yale Cancer Center, New Haven

02215

Dana Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

02100

Rigshospitalet Uni of Hospital of Copenhagen, Copenhagen

05000

Odense University Hospital, Odense C

1066 CX

Netherlands Cancer Institute Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam

9713GZ

University Medical Center Groningen, Groningen

3015 GD

Erasmus Medical Center, Rotterdam

05021

Haukeland University Hospital, Bergen

00379

Utprøvingsenheten, Oslo University Hospital Radiumhospitalet, Oslo

171 76

Karolinska University Hospital Solna, Stockholm

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Incyte Corporation

INDUSTRY