371
Participants
Start Date
March 21, 2018
Primary Completion Date
May 31, 2026
Study Completion Date
May 31, 2026
Oral capsaicin
Subjects will drink a solution with capsaicin
Topical capsaicin
Capsaicin cream will be applied to the skin of the forehead, cheek, or leg
Intranasal capsaicin
Capsaicin cream will be applied to the nostril
Cold Water Irrigation
Subjects will be asked to drink up to 2000 ml of cold water or ice water (temperature 0-10 degrees Celsius) as fast as possible, either continuously or intermittently (i.e. 200-800 ml at a time)
Medical Air
Subjects will be exposed to medical air
Low Flow Oxygen
Subjects will be exposed to oxygen gas between 1-9 L/min
High Flow Oxygen
Subjects will be exposed to oxygen gas between 10-25 L/min
The University of Texas Health Science Center at Houston, Houston
University of California, San Francisco
OTHER
The University of Texas Health Science Center, Houston
OTHER