Parasitic Ulcer Treatment Trial Pilot

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

January 1, 2018

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Acanthamoeba Keratitis
Interventions
DRUG

Chlorhexidine

1 drop half-hourly for days 1-2, then hourly for days 3-6, then 8 times daily until the 4-week visit

DRUG

Povidone-Iodine

1 drop half-hourly for days 1-2, then hourly for days 3-6, then 8 times daily until the 4-week visit

DRUG

Prednisolone Sodium Phosphate

1 drop 4 times daily for weeks 4-9, then 2 times daily for weeks 10-11

DRUG

Hydroxypropyl Methylcellulose

1 drop 4 times daily for weeks 4-9, then 2 times daily for weeks 10-11

DRUG

Prednisolone Sodium Phosphate

1 drop 4 times daily for weeks 6-9, then 2 times daily for weeks 10-11

DRUG

Hydroxypropyl Methylcellulose

1 drop 4 times daily for weeks 4-5

Trial Locations (2)

Unknown

Aravind Eye Hospital, Coimbatore

Aravind Eye Hospital, Madurai

All Listed Sponsors
collaborator

Research to Prevent Blindness

OTHER

lead

University of California, San Francisco

OTHER