Prospective Phenotyping of Autonomous Aldosterone Secretion

Active, not recruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

June 15, 2018

Primary Completion Date

April 1, 2026

Study Completion Date

July 1, 2029

Conditions
Aldosterone DisorderAdrenal Gland DiseaseBlood Pressure
Interventions
DIETARY_SUPPLEMENT

Sodium loaded diet

At baseline, and annually, participants will undergo aldosterone dynamic testing after \~5 days of a sodium loaded diet. The diet will consist of \>180 mmol/day of sodium, \~50 mmol/day of potassium, and 600mg/d of calcium.

DIETARY_SUPPLEMENT

Restricted sodium diet

At baseline, and annually, participants will undergo aldosterone dynamic testing after \~5 days of a sodium restricted diet. The diet will consist of \<40 mmol/day of sodium, \~50 mmol/day of potassium, and 600mg/d of calcium.

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

Brigham and Women's Hospital

OTHER

NCT03484130 - Prospective Phenotyping of Autonomous Aldosterone Secretion | Biotech Hunter | Biotech Hunter