31
Participants
Start Date
March 1, 2018
Primary Completion Date
July 1, 2026
Study Completion Date
December 1, 2026
automated abdominal binder
The binder automatically inflates every time the participant stands up to apply a compression level of about 40 mmHg. Participants will wear the device throughout the active/sham study day.
Sham binder
The binder automatically inflates every time the participant stands up to apply a compression level of about 5 mmHg. Participants will wear the device throughout the active/sham study day.
Placebo
Oral placebo will be given three times a day on the baseline day (placebo)
Midodrine
A midodrine pill 10mg will be given three times a day on the standard of care study day
RECRUITING
Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Vanderbilt University Medical Center
OTHER