Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

September 11, 2018

Primary Completion Date

March 30, 2026

Study Completion Date

March 30, 2026

Conditions
Mantle Cell LymphomaB Cell Lymphoma
Interventions
DRUG

Palbociclib

Taken at 100 mg once daily for 21 days, followed by 7 days off

DRUG

Ibrutinib

560 mg taken orally all patients throughout the study

Trial Locations (9)

10065

Weill Cornell Medical College, New York

14263

Roswell Park Comprehensive Cancer Center, Buffalo

21201

University of Maryland, Greenebaum Comprehensive Cancer Center, Baltimore

27599

University of North Carolina, Chapel Hill

29425

Medical University of South Carolina - Hollings Cancer Center, Charleston

43210

Ohio State University, Columbus

48197

St. Joseph Mercy Hospital Cancer Care Center, Ypsilanti

91010

City of Hope National Medical Center, Duarte

02114

Massachusetts General Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Alliance Foundation Trials, LLC.

OTHER

NCT03478514 - Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma | Biotech Hunter | Biotech Hunter