280
Participants
Start Date
June 10, 2018
Primary Completion Date
May 31, 2021
Study Completion Date
May 31, 2024
Tenofovir Disoproxil Fumarate (TDF) 300 mg oral daily.
All mothers will receive TDF therapy. However, group A will initiate TDF at the gestational week of 14-16, while group B will initiate TDF at the gestational week of 28. All infants will receive a series of three hepatitis B vaccines (at birth, age of weeks 4 and 24). In addition, the infants in the group B will receive HBIg injection at birth.
RECRUITING
Beijing Youan Hospital, Capital Medical University, Beijing
RECRUITING
Southwest Hospital, Chongqing
RECRUITING
Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou
RECRUITING
The Third People's Hospital of Shenzhen, Shenzhen
RECRUITING
Department of Infectious Diseases, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an
RECRUITING
The Fifth Hospital of Shijiazhuang, Shijiazhuang
RECRUITING
Shijiazhuang Maternal and Child Health Care Hospital, Shijiazhuang
Lead Sponsor
New Discovery LLC
INDUSTRY