A Study of CS1003 in Subjects With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

May 9, 2018

Primary Completion Date

May 31, 2021

Study Completion Date

May 31, 2021

Conditions
Advanced Cancer
Interventions
BIOLOGICAL

CS1003

In the dose escalation part, the dose levels will be escalated following a modified 3+3 dose escalation scheme. In the dose expansion part, patients will be assigned to different groups based on their tumor type.

BIOLOGICAL

CS1003

CS1003 to be intravenously administered at the dose level determined during the dose escalation part

DRUG

Regorafenib

Regorafenib to be orally administered at the protocol-specified dose level, once daily for the first 21 days of each 28-day cycle

Trial Locations (1)

2031

Scientia Clinical Research Ltd, Randwick

Sponsors
All Listed Sponsors
lead

CStone Pharmaceuticals

INDUSTRY