Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)

PHASE4CompletedINTERVENTIONAL
Enrollment

270

Participants

Timeline

Start Date

May 1, 2018

Primary Completion Date

April 19, 2022

Study Completion Date

April 19, 2022

Conditions
Hepatitis B, Chronic
Interventions
DRUG

Tenofovir Alafenamide

Tenofovir alafenamide (TAF) is a new formulation of tenofovir with higher intracellular active drug concentration allowing for dosing of only 25 mg once daily and thus can potentially lower the already low risk of renal toxicity and bone loss with tenofovir disoproxil fumarate (TDF).

Trial Locations (12)

807

Kaohsiung Medical University Hospital, Kaohsiung City

82445

E-Da Hospital, Kaohsiung City

94304

Stanford University Medical Center, Palo Alto

95128

San Jose Gastroenterology, San Jose

812-8582

Kyushu University Hospital, Fukuoka

467-8601

Nagoya City University, Nagoya

545-8585

Osaka City University, Osaka

849-8501

Saga University Hospital, Saga

04736

Hanyang University Seoul Hospital, Seoul

Unknown

Nowon Eulji Medical Center, Eulji University College of Medicine,, Seoul

Sanggye Paik Hospital, Inje University College of Medicine, Seoul

China Medical University Hospital, Taichung

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Gilead Sciences

INDUSTRY

lead

Stanford University

OTHER