NCT03467386View on ClinicalTrials.gov

Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

March 19, 2018

Primary Completion Date

April 6, 2026

Study Completion Date

April 6, 2026

Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE

Allogeneic Hematopoietic Stem Cell Transplantation

Undergo alloHCT

DRUG

Cyclophosphamide

Given IV

BIOLOGICAL

Filgrastim

Administer according to City of Hope standard operating procedures

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

DRUG

Tacrolimus

Given CIV

RADIATION

Total Marrow Irradiation

Undergo TMLI

Trial Locations (1)

91010

RECRUITING

City of Hope Medical Center, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER