Signal TrAnsduction Pathway Activity Analysis in OVarian cancER

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

148

Participants

Timeline

Start Date

January 31, 2023

Primary Completion Date

October 1, 2026

Study Completion Date

October 1, 2026

Conditions
Recurrent Ovarian CancerSignal Transduction Pathway DeregulationTherapy-Associated Cancer
Interventions
DRUG

Letrozole Oral Product

Letrozole 2.5mg tablet - 2.5mg once dailty until progression of disease.

DRUG

Bicalutamide Oral Product

Bicalutatmide 150mg tablet - 150mg once daily until progression of disease.

DRUG

Everolimus Oral Product

Everolimus 10mg tablet - 10mg once daily until progression of disease.

DRUG

Itraconazole Oral Product

Itraconazole 100mg capsule - 300mg twice daily until progression of disease.

Trial Locations (6)

Unknown

NOT_YET_RECRUITING

Radboudumc, Nijmegen

NOT_YET_RECRUITING

Erasmus MC, Rotterdam

5623EJ

RECRUITING

Catharina Ziekenhuis, Eindhoven

4818 CK

NOT_YET_RECRUITING

Amphia Hospital, Breda

6229 HX

NOT_YET_RECRUITING

Maastricht UMC+, Maastricht

5022 GC

NOT_YET_RECRUITING

Elisabeth-Tweesteden Hospital, Tilburg

All Listed Sponsors
collaborator

Radboud University Medical Center

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Maastricht University Medical Center

OTHER

collaborator

InnoSIGN

UNKNOWN

collaborator

Eurofins

INDUSTRY

lead

Gynaecologisch Oncologisch Centrum Zuid

OTHER