Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men

PHASE2UnknownINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 16, 2018

Primary Completion Date

March 31, 2020

Study Completion Date

June 30, 2020

Conditions
HealthyMenMale Contraception
Interventions
DRUG

Dimethandrolone-Undecanoate

Single doses of DMAU in castor oil/benzyl benzoate administered in 100 mg capsules.

DRUG

Levonorgestrel 0.03 MG

Single doses of LNG administered in 30 mcg capsules.

DRUG

Placebo oral capsule

Placebo capsules that look like DMAU and LNG capsules but with no active ingredients.

Trial Locations (2)

90509

RECRUITING

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance

98195

RECRUITING

University of Washington Medical Center & Health Sciences, Seattle

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

OTHER

collaborator

University of Washington

OTHER

lead

Premier Research

OTHER