NCT03453944 - NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 9, 2017

Primary Completion Date

July 1, 2018

Study Completion Date

December 31, 2018

Conditions

Mechanical Ventilation ComplicationNeuromuscular Electrical StimulationMuscle Weakness

Interventions

DEVICE

VentFree prototype (VF03-K) active stimulation

Abdominal wall muscle stimulation synchronised with mechanical ventilation. Stimulation frequency: 30 Hz, pulse width: 352us, max. intensity: 100mA (threshold intensity determined using ultrasound)

DEVICE

VentFree prototype (VF03-K) sham stimulation

Abdominal wall muscle sham-stimulation synchronised with mechanical ventilation. Stimulation frequency: 10 Hz, pulse width: 352us, intensity: 15 mA.

Trial Locations (3)

6525 GA

RECRUITING

UMC Nijmegen, Nijmegen

6532 SZ

RECRUITING

Canisius Wilhelmina Hospital, Nijmegen

1081 HV

RECRUITING

VU University Medical Center, Amsterdam