Fluoxetine Opens Window to Improve Motor Recovery After Stroke

PHASE2CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

January 1, 2019

Primary Completion Date

September 30, 2022

Study Completion Date

September 30, 2022

Conditions
StrokeCerebrovascular AccidentCerebral InfarctionBrain InfarctionBrain IschemiaCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular Diseases
Interventions
DRUG

Fluoxetine Hydrochloride

Half of the participants will take fluoxetine for a period of 15-17 weeks (depending on ramp-up period).

OTHER

Placebo

Half of the participants will take the a placebo for a period of 15-17 weeks (depending on ramp-up period).

BEHAVIORAL

Exercise Program

All participants will take part in a 12-week exercise program. The program will run 3 times/week, 1 hour/class.

Trial Locations (8)

T2N 2T9

University of Calgary, Calgary

V5Z 2G9

University of British Columbia & GF Strong Centre, Vancouver

R3L 2P4

Riverview Health Centre, Winnipeg

A1A 1E5

Memorial University of Newfoundland, St. John's

B3H 3J5

Dalhousie University, Halifax

N6C 0A7

Parkwood Institute, London

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

M5G 2A2

Toronto Rehabilitation Institute - University Health Network, Toronto

Sponsors
All Listed Sponsors
collaborator

University of British Columbia

OTHER

collaborator

Sunnybrook Health Sciences Centre

OTHER

collaborator

University of Calgary

OTHER

collaborator

Dalhousie University

OTHER

collaborator

Parkwood Hospital, London, Ontario

OTHER

collaborator

Riverview Health Centre Foundation

OTHER

collaborator

Memorial University of Newfoundland

OTHER

collaborator

Applied Health Research Centre

OTHER

collaborator

Brain Canada

OTHER

collaborator

Heart and Stroke Foundation Canadian Partnership for Stroke Recovery

UNKNOWN

lead

University Health Network, Toronto

OTHER