Safety, Tolerability and Pharmacodynamics of SYNB1020

SYNB1020 was supplied at a concentration of approximately 1 × 10\^11 CFU/mL in a buffered solution in 5 mL cryovials with a nominal 5 mL fill volume, administered with 100 mL of masking buffer solution.

Subjects received placebo orally in a chilled buffered solution (100 mL).