Vasopressin and Pain Perception in the Brain

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 17, 2018

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Acute Pain
Interventions
DRUG

Arginine vasopressin

Intranasal vasopressin will be administered shortly before the fMRI experiment.

OTHER

Saline

Intranasal saline will serve as a placebo for participants in the Saline Arm

BEHAVIORAL

Observational learning

During the observational learning intervention, participants will learn the experience of analgesia in another person via a video. Participants will learn the analgesia nature of the placebo cream and the neutral nature of the control cream.

OTHER

fMRI data aquisition

All participants from the intranasal vasopressin and intranasal saline groups will go through a fMRI data acquisition to obtain the brain structural, brain resting-states and functional MRI scans.

Trial Locations (1)

21201-1512

Luana Colloca, Baltimore

All Listed Sponsors
lead

University of Maryland, Baltimore

OTHER

NCT03446456 - Vasopressin and Pain Perception in the Brain | Biotech Hunter | Biotech Hunter