Start Date
March 16, 2018
Primary Completion Date
October 10, 2018
Study Completion Date
October 10, 2018
IONIS-FB-Lrx
Single Dose of IONIS-FB-Lrx administered once weekly for weeks 1-3, and every other week or less frequently until week 70
Placebo (sterline saline 0.9%)
Calculated volume to match active comparator. Administered subcutaneously weekly for weeks 1-3, and every other week or less frequently until week 70
Auckland Eye, Auckland
Sydney Eye Hospital, Sydney
Sydney Retina Clinic Day Surgery, Sydney
Strathfield Retina Clinic, Strathfield
Marsden Eye Specialists, Paramatta
IONIS Investigational Site, Liverpool
Eye Clinic Albury Wodonga, Albury
The Royal Victorian Eye and Ear Hospital, East Melbourne
Eye Surgery Associates, Parkville
Eye Surgery Associates, Malvern
Retinology Institute, Glen Iris
Royal Adelaide Hospital, Adelaide
Lions Eye Institute, Nedlands
IONIS Investigative Site, New York
IONIS Investigative Site, Pittsburgh
IONIS Investigative Site, Philadelphia
IONIS Investigational Site, Ladson
IONIS Investigational Site, Augusta
IONIS Investigational Site, Tampa
IONIS Investigative Site, Clearwater
IONIS Investigative Site, Chesterfield
IONIS Investigational Site, Leawood
IONIS Investigational Site, Austin
IONIS Investigational Site, Beverly Hills
IONIS Investigative Site, Encino
IONIS Investigative Site, Irvine
IONIS Investigational Site, Santa Barbara
IONIS Investigational Site, Mountain View
IONIS Investigative Site, Phoenix
IONIS Investigative Site, Philadelphia
IONIS Investigative Site, Rapid City
IONIS Investigative Site, Arlington
IONIS Investigative Site, Dallas
IONIS Investigative Site, Houston
IONIS Investigative Site, McAllen
IONIS Investigative Site, San Antonio
IONIS Investigative Site, The Woodlands
Lead Sponsor
Ionis Pharmaceuticals, Inc.
INDUSTRY