Telerehabilitation in Multiple Sclerosis

NAActive, not recruitingINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

February 26, 2018

Primary Completion Date

December 31, 2018

Study Completion Date

June 30, 2024

Conditions
Multiple Sclerosis
Interventions
BEHAVIORAL

VRRS Khymeia

"Participants will receive an individualized exercise program set up by the therapist. The intervention applied to the experimental group will consist of 30 sessions of Khymeia VRRS training distributed in five sessions for week, each lasting 45 minutes.~Each session is constructed by alternating physical with cognitive activities. The sessions will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."

BEHAVIORAL

Usual care program

The usual care group will have written, home-based exercise program, provided to them at an initial face-to-face assessment.

BEHAVIORAL

VRRS Khymeia plus active tDCS

"Participants will receive 5 sessions each lasting 45 minutes of an individualized home-based VRRS training combined with active (anodal) tDCS applied to the left dorsolateral prefrontal cortex over 1 week, followed by 5 weeks of home-based VRRS training.~The sessions of VRRS will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."

BEHAVIORAL

VRRS Khymeia plus placebo tDCS

"Participants will receive 5 sessions each lasting 45 minutes of an individualized home-based VRRS training combined with active (anodal) tDCS applied to the left dorsolateral prefrontal cortex over 1 week, followed by 5 weeks of home-based VRRS training.~The sessions of VRRS will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."

Trial Locations (1)

20148

Irccs Fondazione Don Carlo Gnocchi, Milan

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

IRCCS Centro Neurolesi Bonino Pulejo

OTHER

collaborator

Fondazione Mondino

OTHER

collaborator

IRCCS San Camillo, Venezia, Italy

OTHER

collaborator

IRCCS San Raffaele Roma

OTHER

collaborator

Istituti Clinici Scientifici Maugeri SpA

OTHER

lead

Fondazione Don Carlo Gnocchi Onlus

OTHER