136
Participants
Start Date
February 26, 2018
Primary Completion Date
December 31, 2018
Study Completion Date
June 30, 2024
VRRS Khymeia
"Participants will receive an individualized exercise program set up by the therapist. The intervention applied to the experimental group will consist of 30 sessions of Khymeia VRRS training distributed in five sessions for week, each lasting 45 minutes.~Each session is constructed by alternating physical with cognitive activities. The sessions will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."
Usual care program
The usual care group will have written, home-based exercise program, provided to them at an initial face-to-face assessment.
VRRS Khymeia plus active tDCS
"Participants will receive 5 sessions each lasting 45 minutes of an individualized home-based VRRS training combined with active (anodal) tDCS applied to the left dorsolateral prefrontal cortex over 1 week, followed by 5 weeks of home-based VRRS training.~The sessions of VRRS will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."
VRRS Khymeia plus placebo tDCS
"Participants will receive 5 sessions each lasting 45 minutes of an individualized home-based VRRS training combined with active (anodal) tDCS applied to the left dorsolateral prefrontal cortex over 1 week, followed by 5 weeks of home-based VRRS training.~The sessions of VRRS will initially be tailored to the patient's baseline characteristics. Remotely, the therapist will then adjust the participant's exercise program as appropriate, by changing exercises, level of difficulty or number of repetitions."
Irccs Fondazione Don Carlo Gnocchi, Milan
Collaborators (1)
IRCCS Centro Neurolesi Bonino Pulejo
OTHER
Fondazione Mondino
OTHER
IRCCS San Camillo, Venezia, Italy
OTHER
IRCCS San Raffaele Roma
OTHER
Istituti Clinici Scientifici Maugeri SpA
OTHER
Fondazione Don Carlo Gnocchi Onlus
OTHER