NCT03439865View on ClinicalTrials.gov

Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 2, 2019

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Chronic Rhinosinusitis (Diagnosis)
Interventions
DRUG

Ivacaftor

150 mg tablet PO BID x 14 days

DRUG

standard of care treatment

topical nasal steroid spray and culture-directed antibiotics x 14 days

Trial Locations (1)

35233

RECRUITING

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Alabama at Birmingham

OTHER