Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 15, 2018

Primary Completion Date

February 29, 2020

Study Completion Date

April 11, 2022

Conditions
Cancer
Interventions
DRUG

Nivolumab

Nivolumab 240 mg given by intravenous infusion every 2 weeks

DRUG

Cabiralizumab

Cabiralizumab 4 mg/kg given by intravenous infusion every 2 weeks

DRUG

Urelumab

Urelumab 8 mg given by intravenous infusion every 4 weeks

RADIATION

Stereotactic Body Radiation Therapy

Radiation to metastatic lesion(s) given at assigned dose levels based on lesion location and dose level being tested at time of enrollment. Doses range from 30 - 50 Gy.

Trial Locations (1)

60637

University of Chicago Medical Center, Chicago

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

University of Chicago

OTHER