30
Participants
Start Date
January 29, 2018
Primary Completion Date
May 21, 2019
Study Completion Date
May 21, 2019
Vitamin D3, 10000 Intl Units Oral Capsule
"Vitamin D capsule. Over-encapsulated to mimic placebo oral capsule.~Eligible study participants will be randomized 1:1 to vitamin D or placebo one capsule daily from week 0 to week 24. All participants will be advised to achieve 1 gram daily dietary calcium intake whilst on study.~Blood and urine will be taken at 0, 12, 24 and 36 weeks to evaluate the primary and secondary endpoints.~Rectal swabs will be taken at 0, 24 and 36 weeks.~All participants will continue antiretroviral therapy throughout the study."
Placebo oral capsule
"Capsule containing oleic acid. Over-encapsulated to mimic vitamin D3 capsule.~Eligible study participants will be randomized 1:1 to vitamin D or placebo one capsule daily from week 0 to week 24. All participants will be advised to achieve 1 gram daily dietary calcium intake whilst on study.~Blood and urine will be taken at 0, 12, 24 and 36 weeks to evaluate the primary and secondary endpoints.~Rectal swabs will be taken at 0, 24 and 36 weeks.~All participants will continue antiretroviral therapy throughout the study."
The Peter Doherty Institute for Infection and Immunity, Melbourne
The Alfred Hospital - Department of Infectious Diseases, Melbourne
Royal Melbourne Hospital, Melbourne
Melbourne Sexual Health Centre, Melbourne
Collaborators (1)
Melbourne Health
OTHER
The Alfred
OTHER
Melbourne Sexual Health Centre
UNKNOWN
University of Illinois at Chicago
OTHER
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
University of Melbourne
OTHER