40
Participants
Start Date
March 1, 2015
Primary Completion Date
March 31, 2018
Study Completion Date
March 31, 2018
Repetitive Transcranial Magnetic Stimulation
Patients randomised in Arm 1 will receive stimulation of the dorsolateral prefrontal cortex (frequency 25 Hz; 300 pulses; 80% resting motor threshold=RMT) and primary auditory cortex on both sides (1 Hz; 1000 pulses; 110% RMT) will be stimulated in patients in rTMS stimulation group for 5 consecutive days. No medication therapy will be provided for patients in this arm.
Sham stimulation
Sham stimulation will be performed in patients randomised in Arm 2 of the study for 5 consecutive days. No medication therapy will be provided for patients in this arm.
Ginkgo Biloba Extract
Patients randomised in Arm 3 of the study will receive medication therapy with Ginkgo biloba extract EGb 761 once a day for 6 months.
University Hospital Ostrava, Ostrava
University Hospital Ostrava
OTHER