Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

February 15, 2018

Primary Completion Date

November 6, 2025

Study Completion Date

November 6, 2025

Conditions
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia
Interventions
PROCEDURE

Biospecimen Collection

Undergo collection of bone marrow and blood samples

PROCEDURE

Dual-Energy Computed Tomography

Undergo DECT

DRUG

Fluorothymidine F-18

Undergo FLT PET

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Magnetic Resonance Imaging

Undergo water-fat MRI

PROCEDURE

Positron Emission Tomography

Undergo FLT PET

Trial Locations (1)

91010

RECRUITING

City of Hope Medical Center, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER