A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

February 5, 2018

Primary Completion Date

April 18, 2018

Study Completion Date

April 18, 2018

Conditions
Coronary Artery Disease
Interventions
DRUG

Form 1 of AZD5718 tablets

The participants will be dosed with Form 1 of AZD5718 following an overnight fast of at least 10 hours.

DRUG

Form 2 of AZD5718 tablets

The participants will be dosed with Form 2 of AZD5718 following an overnight fast of at least 10 hours.

DRUG

Form 3 of AZD5718 tablets

The participants will be dosed with Form 3 of AZD5718 following an overnight fast of at least 10 hours.

DRUG

Form 4 of AZD5718 tablets

The participants will be dosed with Form 4 of AZD5718 following an overnight fast of at least 10 hours.

DRUG

Form 5 of AZD5718 tablets

The participants will be dosed with Form 5 of AZD5718 following an overnight fast of at least 10 hours.

DRUG

Selected form (Form 2 - 5) of AZD5718 tablets

The participant will be administered with selected form (one of Form 2-5) of AZD5718 tablets 30 minutes after start of the meal.

Trial Locations (1)

HA1 3UJ

Research Site, London

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY

NCT03420092 - A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers | Biotech Hunter | Biotech Hunter