An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

February 20, 2018

Primary Completion Date

February 1, 2021

Study Completion Date

December 28, 2022

Conditions
Colorectal Cancer
Interventions
BIOLOGICAL

Nivolumab

Specified dose on specified days

DRUG

Oxaliplatin

Specified dose on specified days

DRUG

Leucovorin

Specified dose on specified days

DRUG

Fluorouracil

Specified dose on specified days

DRUG

Bevacizumab

Specified dose on specified days

Trial Locations (49)

10016

Local Institution - 0046, New York

13790

Local Institution - 0031, Johnson City

15212

Local Institution - 0024, Pittsburgh

19104

Local Institution - 0005, Philadelphia

20817

Local Institution - 0021, Bethesda

23229

Local Institution - 0025, Richmond

24014

Local Institution - 0028, Roanoke

28034

Local Institution - 0042, Madrid

28222

Local Institution - 0041, Majadahonda - Madrid

28262

Levine Cancer Institute, Charlotte

33176

Local Institution - 0039, Miami

33705

Local Institution - 0047, St. Petersburg

37203

Local Institution - 0019, Nashville

37403

Erlanger Oncology & Hematology - Univ. of TN, Chattanooga

46260

Local Institution - 0044, Indianapolis

53705

Local Institution - 0006, Madison

55404

Local Institution - 0035, Minneapolis

55905

Local Institution - 0002, Rochester

57104

Local Institution - 0023, Sioux Falls

60005

Local Institution - 0033, Arlington Heights

68046

Local Institution - 0032, Papillion

75246

Local Institution - 0034, Dallas

75702

Local Institution - 0036, Tyler

76022

Local Institution - 0026, Bedford

76104

Local Institution - 0037, Fort Worth

78217

Local Institution - 0040, San Antonio

80045

Local Institution - 0010, Aurora

80218

Local Institution - 0027, Denver

89074

Local Institution - 0029, Henderson

90033

Local Institution - 0004, Los Angeles

97227

Local Institution - 0038, Portland

2778577

Local Institution - 0051, Kashiwa-shi

4118777

Local Institution - 0050, Sunto-gun

4648681

Local Institution - 0055, Nagoya

35294-3300

Uab Comprehensive Cancer Center, Birmingham

06520

Local Institution - 0020, New Haven

02114

Local Institution - 0003, Boston

Local Institution - 0049, Boston

Local Institution - 0052, Boston

Local Institution - 0053, Boston

T6G 1Z2

Local Institution - 0017, Edmonton

K1H 8L6

Local Institution - 0015, Ottawa

M5G 2M9

Local Institution - 0014, Toronto

H2X 1P1

Local Institution - 0048, Montreal

G1J 1Z4

Local Institution - 0012, Québec

J1H 5N4

Local Institution - 0013, Sherbrooke

G8Z 3R9

Local Institution - 0016, Trois-Rivières

00927

Local Institution - 0009, San Juan

08035

Local Institution - 0043, Barcelona

Sponsors
All Listed Sponsors
collaborator

Ono Pharmaceutical Co. Ltd

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY