Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy

CompletedOBSERVATIONAL
Enrollment

25

Participants

Timeline

Start Date

October 1, 2013

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
Carotid StenosisIschemia Reperfusion Injury
Interventions
PROCEDURE

Carotid artery stenting

Patient undergo elective carotid artery stenting. In this patient group blood sampling was performed at three time points: T1, at the time of the insertion of the arterial line; T2, 60 min after stent insertion; and T3: the first postoperative morning.

PROCEDURE

Carotid endarterectomy

Patient undergo elective carotid endarterectomy. Group samples were collected at the following four time points: T1, at the time of the insertion of the arterial line; T2, 60 min after cross-clamp release; T3, the first postoperative morning; and T4, the third postoperative morning. A matched subgroup of patients from the previously obtained data served as a historical control.

Trial Locations (1)

H-7624

Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs, Pécs

All Listed Sponsors
lead

University of Pecs

OTHER

NCT03410576 - Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy | Biotech Hunter | Biotech Hunter